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Last update: May 2021

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Pillar 1 - Risk assessment of the emergence of zoonotic diseases

Ecological, epidemiological and microbiological studies to characterize the emerging risks within human-animal-environment interactions, in areas with a large gradient of human activity in order to concretely quantify their impact on the risk of emergence. Development of disease diagnosis methods based on this knowledge and adapted to needs / field. Socio-economic studies to assess the practices that influence these risks and the levels of ownership of innovations.

Pillar 2 - Reducing the risk of zoonotic emergences by building suitable and resilient socio-ecosystems

By building adapted and resilient socio-ecosystems: participatory workshops with researchers, local communities, and decision-makers to define adapted solutions to reduce risks in the contexts considered (in connection with the data from pillar 1). The objective is to design socio-ecosystems to ensure environmental protection with little affected economic activity and a significantly reduced risk of emergence (winwin- win strategy). These socio-ecosystems can be improved iteratively depending on the evaluation of their efficiency (pillar 3).

Pillar 3 - Socio-economic assessment and implementation of surveillance and early detection strategies

Assessment of current monitoring systems, taking into account pressures on biodiversity; the socio-economic impact of surveillance strategies and response methods; strengthening of diagnostic capacities in laboratories (deployment of tests adapted to the field, technical training; participatory workshops for the co-development of early detection systems adapted to each context; innovative training on good health surveillance practices involving human sectors, animals and environmental; real-time data collection and management systems using remote sensing, or based on smartphone applications (or others depending on the context). This work will be based in particular on the results from pillars 1 and 2.

Pillar 4 - Prototyping a global information system for surveillance and early detection

Development of a new alliance for international scientific collaboration between Europe, Africa, Asia, and the Americas - building on existing scientific networks; development of a system for collecting, analyzing, and managing data in real-time at the international level; analysis of data from national surveillance systems, but also big data from the Internet and from multiple sources using innovative approaches, for example, artificial intelligence. Approaches based on participatory science will also be developed, similar to the existing system for human diseases (PROMED) - in connection with pillar 3. These information systems will be interfaced with those piloted by international organizations managing official data. and warning systems (in particular OIE-Wahis and Glews +, etc.).

Pillar 5 (cross-cutting) – Capacity building and health network strengthening

Stakeholder engagement and development/consolidation of health networks and policies, development of platforms for permanent dialogue between scientists, society, and decision-makers; mapping of key players; participatory workshops and training; innovative approaches to raising awareness, eg. serious games. Development of One-Health training standardized and approved by international organizations for researchers and local public health authorities. Development of centers of excellence for each region to allow the design of adapted and resilient socio-ecosystems by researchers and local decision-makers (iteration pillar 2).

Expected outputs

The 5 pillars will be implemented jointly and in synergy, pillars 1) 2) and 3) being closely interwoven and leading to pillar 4, and pillar 5 being transversal. The expected results are a better understanding and management of risk factors by the local stakeholders (Result 1); the adhesion and implementation by local and national stakeholders to health and conservation policies they have jointly developed (Result 2); the operationality of a real-time health surveillance system from local to the global within a One Health collaboration (Result 3); a permanent and constructive science-society-policy dialog to ensure the development of health policies adapted to the social and economic contexts (Result 4).